Alessandro Pigoni

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Clinical stratification of Major Depressive Disorder in the UK Biobank: A gene-environment-brain Topological Data Analysis

Sep 22, 2024 | medrxiv.org | Emma Tassi |Alessandro Pigoni |Nunzio Turtulici |Federica Colombo

The authors have declared no competing interest. This research has been conducted using the UK Biobank Resource under Application Number 56514 Stratification of health outcomes in mood disorders. The study was supported by the Italian Ministry of Health (DEPTYPE project grant n. GR201912370616).
Psychosis brain subtypes validated in first-episode cohorts and related to illness remission: results from the PHENOM consortium - Molecular Psychiatry

May 5, 2023 | nature.com | Dominic B. Dwyer |Alessandro Pigoni |Junhao Wen |Gyujoon Hwang |Guray Erus |René S. Kahn | +11 more

AbstractUsing machine learning, we recently decomposed the neuroanatomical heterogeneity of established schizophrenia to discover two volumetric subgroups—a ‘lower brain volume’ subgroup (SG1) and an ‘higher striatal volume’ subgroup (SG2) with otherwise normal brain structure.

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