Alex Suh

Sep 19, 2024 | ophthalmologyscience.org | John Hong |Elliot H Choi |Alex Suh

Badminton is among the most popular racquet sports played with a projected 339 million active players worldwide.1 With an increasing number of players each year, the incidence of badminton-related injuries is expected to rise, with injuries to the eye being among the most devastating.

Jul 21, 2024 | nature.com | Joshua Ong |Benjamin Soares |Ethan Waisberg |Alex Suh |Ritu Sampige |Tuan Nguyen | +3 more

Human spaceflight, particularly for long-duration missions, poses significant challenges to astronaut health and well-being. Understanding the impact of spaceflight on the human body is paramount to ensuring the success and safety of such endeavours [1, 2]. In addition to the neuro-ophthalmic findings of spaceflight associated neuro-ocular syndrome (SANS), there are also effects on the anterior segment including increased risk for cataract and dry eye symptoms [3, 4].

Jun 10, 2024 | nature.com | Alex Suh |Joshua Ong |Sharif Amit Kamran |Ethan Waisberg |Nasif Zaman |Prithul Sarker | +5 more

Multiple Sclerosis (MS) is a chronic autoimmune demyelinating disease of the central nervous system (CNS) characterized by inflammation, demyelination, and axonal damage. Early recognition and treatment are important for preventing or minimizing the long-term effects of the disease. Current gold standard modalities of diagnosis (e.g., CSF and MRI) are invasive and expensive in nature, warranting alternative methods of detection and screening. Oculomics, the interdisciplinary combination of ophthalmology, genetics, and bioinformatics to study the molecular basis of eye diseases, has seen rapid development through various technologies that detect structural, functional, and visual changes in the eye. Ophthalmic biomarkers (e.g., tear composition, retinal nerve fibre layer thickness, saccadic eye movements) are emerging as promising tools for evaluating MS progression. The eye’s structural and embryological similarity to the brain makes it a potentially suitable assessment of neurological and microvascular changes in CNS. In the advent of more powerful machine learning algorithms, oculomics screening modalities such as optical coherence tomography (OCT), eye tracking, and protein analysis become more effective tools aiding in MS diagnosis. Artificial intelligence can analyse larger and more diverse data sets to potentially discover new parameters of pathology for efficiently diagnosing MS before symptom onset. While there is no known cure for MS, the integration of oculomics with current modalities of diagnosis creates a promising future for developing more sensitive, non-invasive, and cost-effective approaches to MS detection and diagnosis.

Apr 20, 2024 | nature.com | Alex Suh |Joshua Ong |Ethan Waisberg

Embarking on long-duration spaceflights with limited resources and absence of immediate medical facilities necessitates careful consideration of potential health hazards in the unforgiving confines of space. Among the extensive possible risks inherent in space exploration, ocular injuries [1,2,3], particularly corneal thermal burns, stand out as significant focal points of concern.

Feb 29, 2024 | nature.com | Alex Suh |Joshua Ong |Thomas Mader |Ethan Waisberg

The International Space Station (ISS) is one of the most remote and austere environments in which a human being can live and work. Responding to medical emergencies in such an environment can be extremely difficult.