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Nov 14, 2024 | 
nature.com | Ethan Waisberg |Joshua Ong |Mouayad Masalkhi
Correction to: Eye (2024) 38:2847-2848Affiliation 1 has been corrected from “Department of Ophthalmology, University of Cambridge, Cambridge, UK” to “Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK”. The original article has been corrected.
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Jul 30, 2024 | 
mdpi.com | Ritu Sampige |Joshua Ong |Ethan Waisberg |John Berdahl
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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Jul 23, 2024 | 
nature.com | Ethan Waisberg |Joshua Ong |Mouayad Masalkhi
IntroductionQuantum biology is the application of quantum theory to describe aspects of biology that are insufficiently described by classical laws of physics. This field involves the study of how light interacts with biological systems. Prior to the 20th century, physics and biology rarely intersected and biological systems were thought to be too complex to be represented using mathematical methods [1].
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Jul 21, 2024 | 
nature.com | Joshua Ong |Benjamin Soares |Ethan Waisberg |Alex Suh |Ritu Sampige |Tuan Nguyen | +3 more
Human spaceflight, particularly for long-duration missions, poses significant challenges to astronaut health and well-being. Understanding the impact of spaceflight on the human body is paramount to ensuring the success and safety of such endeavours [1, 2]. In addition to the neuro-ophthalmic findings of spaceflight associated neuro-ocular syndrome (SANS), there are also effects on the anterior segment including increased risk for cataract and dry eye symptoms [3, 4].
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Jul 1, 2024 | 
nature.com | Mouayad Masalkhi |Joshua Ong |Ethan Waisberg
IntroductionQuantum computing (QC) is an advanced field of innovative technology that leverages the principles of quantum mechanics to perform computations far beyond the capabilities of classical computers [1]. At its core, QC utilizes quantum bits (qubits), which unlike classical bits can exist in multiple states (other than 0 and 1 used in traditional computing) simultaneously through superposition [1]. This allows QC to process a vast number of possibilities simultaneously [1].
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Jun 14, 2024 | 
nature.com | Ethan Waisberg |Joshua Ong |Mouayad Masalkhi
Long-duration spaceflight (LDSF) poses significant challenges on the human body, including the emergence of unique physiological conditions such as Spaceflight-Associated Neuro-Ocular Syndrome (SANS, ex. VIIP). SANS is a complex collection of ocular changes observed in astronauts during and after long-duration space missions [1]. Initially identified through post-flight examinations, SANS includes symptoms such as globe flattening [2], choroidal folds [3], and optic disc oedema [4].
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Jun 10, 2024 | 
nature.com | Alex Suh |Joshua Ong |Sharif Amit Kamran |Ethan Waisberg |Nasif Zaman |Prithul Sarker | +5 more
Multiple Sclerosis (MS) is a chronic autoimmune demyelinating disease of the central nervous system (CNS) characterized by inflammation, demyelination, and axonal damage. Early recognition and treatment are important for preventing or minimizing the long-term effects of the disease. Current gold standard modalities of diagnosis (e.g., CSF and MRI) are invasive and expensive in nature, warranting alternative methods of detection and screening. Oculomics, the interdisciplinary combination of ophthalmology, genetics, and bioinformatics to study the molecular basis of eye diseases, has seen rapid development through various technologies that detect structural, functional, and visual changes in the eye. Ophthalmic biomarkers (e.g., tear composition, retinal nerve fibre layer thickness, saccadic eye movements) are emerging as promising tools for evaluating MS progression. The eye’s structural and embryological similarity to the brain makes it a potentially suitable assessment of neurological and microvascular changes in CNS. In the advent of more powerful machine learning algorithms, oculomics screening modalities such as optical coherence tomography (OCT), eye tracking, and protein analysis become more effective tools aiding in MS diagnosis. Artificial intelligence can analyse larger and more diverse data sets to potentially discover new parameters of pathology for efficiently diagnosing MS before symptom onset. While there is no known cure for MS, the integration of oculomics with current modalities of diagnosis creates a promising future for developing more sensitive, non-invasive, and cost-effective approaches to MS detection and diagnosis.
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May 22, 2024 | 
nature.com | Tuan Nguyen |Joshua Ong |Ethan Waisberg
Spaceflight associated neuro-ocular syndrome (SANS) represents a constellation of neuro-ocular changes observed in many astronauts after long-duration spaceflight (LDSF) missions. These findings include optic disc edema (ODE), globe flattening, chorioretinal folds, and a hyperopic refractive shift [1,2,3,4]. One of the hallmark features of SANS is ODE, observed in up to ~70% of all astronauts during LDSF [5].
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May 1, 2024 | 
nature.com | Ethan Waisberg |Joshua Ong |Mouayad Masalkhi
IntroductionSora is a state-of-the-art AI model developed by Open AI that has been engineered to generate realistic and imaginative scenes purely based on textual instructions [1]. This innovative application is a remarkable leap forward and highlights the advanced capabilities of modern AI in interpreting and visualizing complex narratives [1]. The technological foundation of Sora rests on Large Language Models (LLMs) and artificial video generation techniques.
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Apr 20, 2024 | 
nature.com | Alex Suh |Joshua Ong |Ethan Waisberg
Embarking on long-duration spaceflights with limited resources and absence of immediate medical facilities necessitates careful consideration of potential health hazards in the unforgiving confines of space. Among the extensive possible risks inherent in space exploration, ocular injuries [1,2,3], particularly corneal thermal burns, stand out as significant focal points of concern.
