Alexander Loboda

Jan 24, 2025 | digitalcommons.library.tmc.edu | Elizabeth Atkinson |Mykyta Artomov |Alexander Loboda |Heidi Rehm

KeywordsGenotype, Heterozygote, Genetics, Population, Phenotype, Exome, Polymorphism, Single NucleotideAbstractLarge-scale high-throughput sequencing data sets have been transformative for informing clinical variant interpretation and for use as reference panels for statistical and population genetic efforts.

Jan 10, 2024 | nature.com | Mykyta Artomov |Alexander Loboda |Maxim N. Artyomov

AbstractAcquiring a sufficiently powered cohort of control samples matched to a case sample can be time-consuming or, in some cases, impossible. Accordingly, an ability to leverage genetic data from control samples that were already collected elsewhere could dramatically improve power in genetic association studies. Sharing of control samples can pose significant challenges, since most human genetic data are subject to strict sharing regulations.

Mar 25, 2023 | biorxiv.org | Alexander Loboda |Dmitrii Usoltsev |Nikita Kolosov |Oxana Rotar

New Results doi: https://doi.org/10.1101/2023.03.23.534000 AbstractThe population of Russia consists of more than 150 local ethnicities. The ethnic diversity and geographic origins, which extend from eastern Europe to Asia, make the population uniquely positioned to investigate the shared properties of inherited disease risks between European and Asian ethnicities.