Mykyta Artomov

Jan 24, 2025 | digitalcommons.library.tmc.edu | Elizabeth Atkinson |Mykyta Artomov |Alexander Loboda |Heidi Rehm

KeywordsGenotype, Heterozygote, Genetics, Population, Phenotype, Exome, Polymorphism, Single NucleotideAbstractLarge-scale high-throughput sequencing data sets have been transformative for informing clinical variant interpretation and for use as reference panels for statistical and population genetic efforts.

Jan 10, 2024 | nature.com | Mykyta Artomov |Alexander Loboda |Maxim N. Artyomov

AbstractAcquiring a sufficiently powered cohort of control samples matched to a case sample can be time-consuming or, in some cases, impossible. Accordingly, an ability to leverage genetic data from control samples that were already collected elsewhere could dramatically improve power in genetic association studies. Sharing of control samples can pose significant challenges, since most human genetic data are subject to strict sharing regulations.

Jul 11, 2023 | nature.com | Mykyta Artomov

AbstractFamine exposure during early life development can affect disease risk in late-life period, yet, transmission of phenotypic features from famine-exposed individuals to the next generations has not been well characterized. The purpose of our case–control study was to investigate the association of parental starvation in the perinatal period and the period of early childhood with the phenotypic features observed in two generations of descendants of Leningrad siege survivors.