Alice E Kane

Jun 27, 2024 | biorxiv.org | Alice E Kane |Karthikeyani Chellappa |Michael Schultz |Matthew Arnold

AbstractNicotinamide adenine dinucleotide (NAD) is essential for many enzymatic reactions, including those involved in energy metabolism, DNA repair and the activity of sirtuins, a family of defensive deacylases. During aging, levels of NAD+ can decrease by up to 50% in some tissues, the repletion of which provides a range of health benefits in both mice and humans. Whether or not the NAD+ precursor nicotinamide mononucleotide (NMN) extends lifespan in mammals is not known.

Apr 12, 2024 | cell.com | MANISH MISHRA |Judy Wu |Alice E Kane |Susan E. Howlett

Roser M. Ortiz-Ospina E. Ritchie H. Life Expectancy. 2013López-Otín C. Galluzzi L. Freije J.M.P. Madeo F. Kroemer G. Metabolic control of longevity. Cell. 2016; 166: 802-821https://doi.org/10.1016/j.cell.2016.07.031Nutrition, longevity and disease: from molecular mechanisms to interventions. Cell. 2022; 185: 1455-1470https://doi.org/10.1016/j.cell.2022.04.002López-Otín C. Blasco M.A. Partridge L. Serrano M. Kroemer G. Hallmarks of aging: An expanding universe. Cell.

Mar 5, 2023 | palatinate.org.uk | Alice E Kane

By Alice KaneHow to describe Miss Sohee’s designs? Well, your nan would love them, your boyfriend would hate them (this is a good thing) and if you lay down in the garden of Eden wearing one of her dresses, no one would know you were there. Miss Sohee’s opulent evening wear is an ornament to Korean craftsmanship, the female form, and the unnerving beauty of the natural world. Sohee Park, the creative director and founder of Miss Sohee, is only 26 years old.