Allison C. Billi

Jan 16, 2025 | nature.com | Allison C. Billi |J. Michelle Kahlenberg

While the skin is among the most commonly affected organ systems in systemic lupus erythematosus (SLE), the role of the skin in driving disease onset remains unresolved. In their recent work, Tian et al. reported that PPARγ deficiency in keratinocytes (KCs) leads to epidermal hypersecretion of type I IFN. The resulting IFN-rich environment activates local dendritic cells (DCs), which in turn activate autoreactive T cells to precipitate SLE-like autoimmune disease [1].

Dec 1, 2023 | networthynews.com | Allison C. Billi

By Allison C. Billi, MD, PhD, as informed to Jodi HelmerFor the 7.5 million Americans detected with psoriasis, it can be discouraging to hear that there’s no remedy. There are numerous treatments that can assist keep this autoimmune illness under control.

Nov 6, 2023 | webmd.com | Allison C. Billi

By Allison C. Billi, MD, PhD, as told to Jodi HelmerFor the 7.5 million Americans diagnosed with psoriasis, it can be disheartening to hear that there's no cure. But there are several treatments that can help keep this autoimmune disease under control.

Aug 22, 2023 | insight.jci.org | JCI Insight |Allison C. Billi |Rachael Wasikowski |Feiyang Ma

AbstractRisk of severe disease and death due to COVID-19 is increased in certain patient demographic groups, including those of advanced age, male sex, and obese body mass index. Investigations of the biological variations that contribute to this risk have been hampered by heterogeneous severity, with immunologic features of critical disease potentially obscuring differences between risk groups.