Alvar Agusti

2 months ago | publications.ersnet.org | Alvar Agusti |Stefano Aliberti |Pieve Emanuele |Francesco Blasi

Editorial Occluding mucous airway plugs in patients with obstructive lung diseases: a new treatable trait? ArticleFigures & TablesInfo & Metrics Chronic mucous hypersecretion (CMH), often manifested clinically by chronic productive cough (i.e. chronic bronchitis), is a well-described feature in several obstructive lung diseases, including asthma, COPD and bronchiectasis.

Jul 18, 2024 | nature.com | Alvar Agusti

AbstractDespite great advancements in the treatment of chronic airway diseases, improvements in morbidity and mortality have stalled in recent years. Asthma and chronic obstructive pulmonary disease are complex and heterogeneous diseases that require tailored management based on individual patient characteristics and needs.

Mar 29, 2024 | digitalcommons.library.tmc.edu | Helen Reddel |Alvar Agusti |Gary Anderson |Richard Beasley

AbstractAsthma and chronic obstructive pulmonary disease (COPD) have overlapping clinical features and share pathobiological mechanisms but are often considered distinct disorders. Prospective, observational studies across asthma, COPD and asthma-COPD overlap are limited. NOVELTY is a global, prospective observational 3-year study enrolling ∼12 000 patients ≥12 years of age from primary and specialist clinical practices in 19 countries (ClinicalTrials.gov identifier: NCT02760329).

Mar 29, 2024 | digitalcommons.library.tmc.edu | Helen Reddel |Alvar Agusti |Gary Anderson |Richard Beasley

AbstractAsthma and chronic obstructive pulmonary disease (COPD) have overlapping clinical features and share pathobiological mechanisms but are often considered distinct disorders. Prospective, observational studies across asthma, COPD and asthma-COPD overlap are limited. NOVELTY is a global, prospective observational 3-year study enrolling ∼12 000 patients ≥12 years of age from primary and specialist clinical practices in 19 countries (ClinicalTrials.gov identifier: NCT02760329).

Oct 24, 2023 | thelancet.com | Surya P. Bhatt |Richard Casaburi |Alvar Agusti |Bartolome Celli

Chronic obstructive pulmonary disease (COPD) is the third leading cause of death worldwide, with 3·23 million deaths reported in 2019. For a long time, COPD was seen as a disease of smokers—a terminal disease, diagnosed in older people, with few treatment options.