
Amanat Ali
Articles
Identification of functional rare coding variants in IGF-1 gene in humans with exceptional longevity
Oct 13, 2024 |
biorxiv.org | Amanat Ali |Zhengdong Zhang |Tina Gao |Sandra Aleksic
AbstractDiminished signaling via insulin/insulin-like growth factor-1 (IGF-1) axis is associated with longevity in different model organisms. IGF-1 gene is highly conserved across species, with only few evolutionary changes identified in it. Despite its potential role in regulating lifespan, no coding variants in IGF-1 have been reported in human longevity cohorts to date.
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May 21, 2024 |
medrxiv.org | Amanat Ali |Sofiya Milman |Erica Weiss |Tina Gao
The authors have declared no competing interest. This work was supported by R01AG061155 (SM), U19AG056278 (ZDZ), P01AG017242 (ZDZ), and P01AG047200 (ZDZ). I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained.
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Apr 5, 2023 |
dailymotion.com | Amanat Ali
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