Amsterdam Gastroenterology

Apr 17, 2024 | cell.com | Amsterdam Gastroenterology |Amsterdam UMC

Highlights The gut microbiota has been implicated in the multifactorial pathophysiology of cardiometabolic diseases (CMD). Bacteriophage (phage) therapy offers precise modulation of the gut microbiota, targeting specific pathobionts while minimizing collateral damage to beneficial microbes. Studies highlight the therapeutic potential of phages in cardiometabolic diseases, including reductions in pathogenic bacteria and improvements in metabolic parameters.

Jan 30, 2024 | academic.oup.com | Amsterdam Gastroenterology |den Elzen |Amsterdam UMC |Amsterdam Reproduction

Cryoactivation is known to occur in whole blood and plasma samples when kept between +4 and −5 °C, leading to falsely high renin concentrations. In 2022 it has been clearly shown that cryoactivation can also occur in samples stored at −20 °C. Based on these new findings, here we discuss how this can influence the clinical diagnosis of patients.

Oct 5, 2023 | academic.oup.com | Amsterdam Gastroenterology |Amsterdam Reproduction

Androgens are synthesized from cholesterol through sequential conversions by enzymes in the adrenal glands and gonads. Serum levels of androgens change during the different phases of life and regulate important developmental and maturational processes. Androgen excess or deficiency can therefore present at various ages in various ways.