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Jan 16, 2025 | 00338-7/abstract&sz=64)
thelancet.com | Leslie Skeith |Jennifer Donnelly |Amsterdam Reproduction |Stephen Wood
aDivision of Hematology and Hematological Malignancies, Department of Medicine, University of Calgary, Calgary, AB, Canada bDepartment of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, Lunenfeld-Tanenbaum Research Institute, Sinai Health, University of Toronto, Toronto, ON, Canada cDepartment of Obstetrics and Gynecology, University of Ottawa, Ottawa, ON, Canada dDepartment of Medicine, University of Ottawa, Ottawa, ON, Canada eDepartment of Medicine, University of British...
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Jan 5, 2025 | 
jamanetwork.com | Amsterdam Reproduction |Leon de Wit |Ruben G. Duijnhoven |Ben Willem Mol
Question In gestational diabetes, is a sequential oral glucose-lowering medication strategy of metformin and additional glyburide, if needed, noninferior to insulin treatment for prevention of large-for-gestational-age infants? Findings Among 820 participants randomized to oral glucose-lowering medication, 23.9% of infants were large for gestational age compared with 19.9% randomized to insulin, a difference that did not meet the prespecified criteria for noninferiority.
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Nov 29, 2024 | 
obgyn.onlinelibrary.wiley.com | Arda Arduç |Amsterdam Reproduction |Elisabeth van Leeuwen |Ingeborg H. Linskens
What is already known about this topic? ◦ The current Dutch and ISUOG guidelines for the second trimester anomaly scan require sonographers to visualize at least both the upper and lower limbs, along with the posture of the hands and legs. However, visualization of the digits is not explicitly mandated in these guidelines, although it remains an important aspect for thorough fetal assessment. What does this study add?
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Nov 29, 2024 | 
onlinelibrary.wiley.com | Pia Burger |Amsterdam Reproduction |Frea H. Kruisinga |Anneline Lettink
1 INTRODUCTION Polysomnography (PSG) is the gold-standard for measuring sleep and for detecting underlying sleep disruptors such as obstructive sleep apnea, as it can accurately characterize sleep using electroencephalography (EEG). However, PSG is limited by the number of nights that are usually evaluated (typically 1 night), its significant financial costs, and its intrusiveness.
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Nov 25, 2024 | 
obgyn.onlinelibrary.wiley.com | N. Min |Amsterdam Reproduction |J. van Keizerswaard |R. H. Visser
INTRODUCTION Vesicouterine adhesions are adhesions of the anterior compartment between the uterus, bladder and/or anterior abdominal wall. There is an association with chronic pelvic pain, dyspareunia, small bowel obstruction, increased operative difficulty in gynecological surgery and possible infertility1-3. The most common cause of these adhesions is a Cesarean section.
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Nov 25, 2024 | 
academic.oup.com | Amsterdam UMC Location |Amsterdam Reproduction |de Groot
In the early days of human IVF, preimplantation embryos were cultured in fairly simple salt solutions prepared by embryologists themselves. Nowadays, it is common to purchase more complex commercial embryo culture media from various suppliers (Chronopoulou and Harper, 2015).
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Nov 12, 2024 | 00614-6/fulltext?rss=yes&sz=64)
ejog.org | Leah I. Prins |Amsterdam UMC Location |Amsterdam Reproduction
DiscussionThis study reported on prognostic factors of perinatal mortality in eoFGR between 20 and 30 weeks of gestation in a fetus at risk approach, to be used as information for parental counseling in case of eoFGR. Overall, as expected, survival rates were worse at lower EFW ratios, lower FAC ratios, higher UA PI ratios, higher UtA PI and AREDflow in the UA. Also, male sex, non-Caucasian ethnicity and lower PlGF levels were predictors for perinatal mortality.
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Nov 12, 2024 | 
fn.bmj.com | Anne Schoonderwoerd |Amsterdam UMC |Amsterdam Reproduction |Jacqueline Muts
DiscussionThis research project aimed to measure changes in macronutrient composition during an extended lactation period. Besides fundamental scientific interest, our findings could help human milk bank policymakers decide on the eligibility of potential donors throughout prolonged lactation. The study demonstrates that human milk protein levels follow a U-shaped path, dipping between 8 and 18 months after birth.
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Nov 8, 2024 | 
jamanetwork.com | Yousif F. Dawood |Amsterdam Reproduction |Eva PAJKRT
Key PointsQuestion How have parental decisions to donate fetal tissue following termination of pregnancy changed after the introduction of the Dutch Fetal Biobank (DFB), and what factors are associated with consent to donation? Findings In this cohort study of 1272 participants, fetal tissue donations significantly increased from 1.2% to 21.7% after the DFB’s introduction, with 30.3% of informed participants consenting to donate.
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Oct 15, 2024 | 
link.springer.com | Amsterdam Reproduction |Charité-Universitaetsmedizin Berlin |Humboldt-Universitaet zu Berlin
AbstractA series of modifiable lifestyle factors, such as diet quality, physical activity, alcohol intake, and smoking, may drive the rising burden of type 2 diabetes (T2DM) among sub-Saharan Africans globally. It is unclear whether epigenetic changes play a mediatory role in the associations between these lifestyle factors and T2DM. We assessed the associations between a comprehensive lifestyle index, DNA methylation and T2DM among Ghanaian adults.
