Amy Pruden

Jan 14, 2025 | biorxiv.org | Joung Min Choi |Monjura Afrin Rumi |Peter Vikesland |Amy Pruden

AbstractBackground: The global spread of antibiotic resistance presents a significant threat to human, animal, and plant health. Metagenomic sequencing is increas- ingly being utilized to profile antibiotic resistance genes (ARGs) in various environments, but presently a mechanism for predicting future trends in ARG occurrence patterns is lacking.

Sep 23, 2024 | nature.com | Suraj Amar Gupta |Xiaowei Wu |Amy Pruden

AbstractPrior studies have shown that socio-economic indicators collectively explain most of the variance in sewage resistomes. However, the relationship between human faecal and sewage resistomes has not been well characterized.

Sep 11, 2024 | dx.doi.org | Matthew Blair |Emily Garner |Pan Ji |Amy Pruden

IntroductionClick to copy section linkSection link copied!Drinking water and wastewater systems provide rich environments that support taxonomically and functionally diverse microbial populations. (1−4) In the wastewater sector, biological treatment is essential for the removal of biochemical oxygen demand (BOD), nitrogen, (5−7) and phosphorus. (8−12) Microbes in wastewater also contribute to degradation of contaminants of emerging concern.

Jun 19, 2024 | biorxiv.org | James Mullet |Liqing Zhang |Amy Pruden |Connor Brown

AbstractPhage-plasmids are unique mobile genetic elements that function as plasmids and temperate phages. While it has been observed that such elements often encode antibiotic resistance genes and defense system genes, little else is known about other functional traits they encode. Further, no study to date has documented their environmental distribution and prevalence.