Ana Alcaina Caro

Apr 20, 2023 | nature.com | Sudha Rajderkar |Iros Barozzi |Yiwen Zhu |Ana Alcaina Caro |Matthew Blow |Jennifer A. Akiyama | +3 more

ENCODE ChIP-seq data analysis and prioritization of TAD boundary deletion lociPreviously published chromosome conformation capture data was used for combined analyses and selection of TAD boundary deletion loci in this study, wherein TAD boundary calls were based on the maximum enrichment of CTCF at the TAD borders and their consistency across cell-types10. Over 3300 genome-wide annotated TAD boundaries5,10 were then ranked on a weighted score (see Supplementary Fig.