Andrea Gaedigk

Apr 17, 2024 | ascpt.onlinelibrary.wiley.com | Kathryn E. Kyler |Andrea Gaedigk |Susan M. Abdel-Rahman |Vincent S. Staggs

WHAT IS THE CURRENT KNOWLEDGE ON THE TOPIC? A prior study reported a novel CYP2C haplotype (CYP2C:TG) that was functionally similar to that of the increased function CYP2C19*17 allele. The CYP2C:TG haplotype was described to confer increased activity toward CYP2C19 substrates (e.g., escitalopram) similar to that of CYP2C19*17. WHAT QUESTION DID THIS STUDY ADDRESS?