Susan M. Abdel-Rahman

Apr 17, 2024 | ascpt.onlinelibrary.wiley.com | Kathryn E. Kyler |Andrea Gaedigk |Susan M. Abdel-Rahman |Vincent S. Staggs

WHAT IS THE CURRENT KNOWLEDGE ON THE TOPIC? A prior study reported a novel CYP2C haplotype (CYP2C:TG) that was functionally similar to that of the increased function CYP2C19*17 allele. The CYP2C:TG haplotype was described to confer increased activity toward CYP2C19 substrates (e.g., escitalopram) similar to that of CYP2C19*17. WHAT QUESTION DID THIS STUDY ADDRESS?

Apr 15, 2024 | ascpt.onlinelibrary.wiley.com | Susan M. Abdel-Rahman |Andrew J. Farrell |Gilbert J. Burckart |N. Seth Berry

CONFLICT OF INTEREST The authors declared no competing interests for this work. 1Patel, M. & Raphael, J.L. Pediatric subspecialty pipeline: aligning care needs with a changing pediatric health care delivery environment. Pediatr. Res. 93, 1791–1793 (2023). 2Roehrig, C. Mental disorders top the list of the Most costly conditions in the United States: $201 billion. Health Aff. 35, 1130–1135 (2016). 3Lester, H., Tritter, J.Q. & Sorohan, H.