Angela Mastaloudis

Dec 5, 2024 | pubs.rsc.org | Wei Zhu |E. Cremonini |Angela Mastaloudis |Alyson Mitchell

Optimization of sulforaphane bioavailability from a glucoraphanin-rich broccoli seed extract in a model of dynamic gastric digestion and absorption by Caco-2 cell monolayers Broccoli is recognized for its health benefits, attributed to the high concentrations of glucoraphanin (GR). GR must be hydrolyzed by myrosinase (Myr) to form the bioactive sulforaphane (SF). The primary challenge in delivering SF in the upper gastrointestinal (GI) tract, is improving hydrolysis of GR to SF.