E. Cremonini

Dec 5, 2024 | pubs.rsc.org | Wei Zhu |E. Cremonini |Angela Mastaloudis |Alyson Mitchell

Optimization of sulforaphane bioavailability from a glucoraphanin-rich broccoli seed extract in a model of dynamic gastric digestion and absorption by Caco-2 cell monolayers Broccoli is recognized for its health benefits, attributed to the high concentrations of glucoraphanin (GR). GR must be hydrolyzed by myrosinase (Myr) to form the bioactive sulforaphane (SF). The primary challenge in delivering SF in the upper gastrointestinal (GI) tract, is improving hydrolysis of GR to SF.

Sep 6, 2024 | pubs.rsc.org | Giovanni Enrico Lombardo |Michele Navarra |E. Cremonini

A flavonoid-rich extract of bergamot juice improves high-fat diet-induced intestinal permeability and associated hepatic damage in mice Consumption of high-fat diets (HFD) is a contributing factor to obesity, insulin resistance and non-alcoholic fatty liver disease (NAFLD). Several studies suggested a protective role of bioactives present in Citrus fruits against the above mentioned chronic metabolic conditions.

Dec 5, 2023 | pubs.rsc.org | Zahra Mostofinejad |E. Cremonini |Jiye Kang |Patricia Oteiza

Effects of (-)-epicatechin on hepatic triglyceride metabolism (-)-Epicatechin (EC) consumption is associated to an improvement of hyperlipemia and other metabolic changes linked to obesity and western-style diets.