Angela Russell

Nov 7, 2023 | pubs.rsc.org | Sven Epple |Irene Georgiou |Evelyne Gout |Alice Kennett |Angela Russell

Modified minimal-size fragments of Heparan Sulfate as inhibitors of endosulfatase-2 (Sulf-2) Endosulfatase-2 (Sulf-2) has been identified as a putative target for anticancer therapeutics, however, the biological characterisation of this enzyme has been limited by the lack of potent, selective and easily synthesised inhibitors.