Evelyne Gout

Apr 19, 2024 | nature.com | Evelyne Gout |Kristoffer Weißert |Sandra Ammann |Ralf Kühn |Matthias Richter |Christine Molenda | +3 more

Correction to: Nature Immunology https://doi.org/10.1038/s41590-023-01420-5, published online 2 February 2023. In the version of the article initially published, Anja Schütz (Protein Production & Characterization Core Facility, Max-Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany), who produced the recombinant proteins used in this study, was inadvertently omitted from the author list. This has now been corrected in the PDF and HTML versions of the article.

Apr 11, 2024 | pubs.rsc.org | Alice Kennett |Sven Epple |Irene Georgiou |Evelyne Gout

Correction: Modified minimal-size fragments of heparan sulfate as inhibitors of endosulfatase-2 (Sulf-2) Correction for ‘Modified minimal-size fragments of heparan sulfate as inhibitors of endosulfatase-2 (Sulf-2)’ by Alice Kennett et al., Chem. Commun., 2024, 60, 436–439, https://doi.org/10.1039/D3CC02565A. This article is Open Access This article has not yet been cited.

Dec 12, 2023 | pubs.rsc.org | Alice Kennett |Sven Epple |Irene Georgiou |Evelyne Gout

Modified minimal-size fragments of heparan sulfate as inhibitors of endosulfatase-2 (Sulf-2)† Sulf-2 has been identified as a putative target for anticancer therapies. Here we report the design and synthesis of sulfated disaccharide inhibitors based on IdoA(2S)-GlcNS(6S). Trisulfated disaccharide inhibitor IdoA(2S)-GlcNS(6Sulfamate) demonstrated potent Sulf-2 inhibition.

Nov 7, 2023 | pubs.rsc.org | Sven Epple |Irene Georgiou |Evelyne Gout |Alice Kennett |Angela Russell

Modified minimal-size fragments of Heparan Sulfate as inhibitors of endosulfatase-2 (Sulf-2) Endosulfatase-2 (Sulf-2) has been identified as a putative target for anticancer therapeutics, however, the biological characterisation of this enzyme has been limited by the lack of potent, selective and easily synthesised inhibitors.

Feb 22, 2023 | nature.com | Evelyne Gout |Kristoffer Weißert |Sandra Ammann |Ralf Kühn |Matthias Richter |Christine Molenda | +3 more

Correction to: Nature Immunology https://doi.org/10.1038/s41590-023-01420-5. Published online 2 February 2023. In the version of this article originally published, there was an error in the order of magnitude for the units displayed on the y axes of the Figure 4g HBG (g/dl) panel and Figure 4h Triglycerides (mg/dl) panel, where the units now reading “20, 15, 10, 5, 0” and “200, 150, 100, 50, 0” appeared in error as “2,000, 1,500, 1,000, 500, 0” and “20,000, 15,000, 10,000, 5,000, 0,” respectively.