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Dec 25, 2024 | 
acrjournals.onlinelibrary.wiley.com | Yann Nguyen |Hôpital Bicêtre |Assistance Publique
Objective Recently, three distinct phenotypes of patients with Sjögren disease (SjD) have been described based on cluster analysis: B cell active with low symptoms (BALS), high systemic activity (HSA), and low systemic activity with high symptoms (LSAHS). We aimed to assess whether these clusters were associated with distinct biomarkers and the prognostic value of interferon (IFN) signature.
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Nov 13, 2024 | 
jamanetwork.com | Hugo Bottemanne |Assistance Publique |Institut du Cerveau |Lucie Joly
How the Paternal Brain Is Wired by Pregnancy Pregnancy and post partum are accompanied by structural and functional brain changes in women that are thought to be important for caregiving.1 Studies have shown that pregnancy in women is associated with extensive gray matter volume reductions during pregnancy.1 Compared with controls, expecting mothers present lower cortical volume across several brain areas, with fewer cortical differences in the early postpartum period.1 Some of these brain...
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Jul 19, 2024 | 
academic.oup.com | Assistance Publique
Terrorist threats are a worldwide phenomenon. The injuries caused with military weapons or explosives are multiple and unusual for civilian care services. Damage control (DC) training has then become a critical need. In response to the November 2015 attacks, the French authorities launched a national DC training campaign for emergency care personnel.
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Jun 24, 2024 | 
trialbulletin.com | Assistance Publique
OverviewChildhood interstitial lung diseases (chILD) are a heterogeneous group of rare and severe
disorders with an estimated prevalence of 1/100,000. Among them, neuroendocrine cells
hyperplasia of infancy (NEHI), also called persistent tachypnoea of infancy (PTI), is one of
the most common aetiology (up to 16% of the cases).
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Jun 24, 2024 | 
trialbulletin.com | Assistance Publique
OverviewThe main objective of this study is to estimate the prevalence of Pediatric Eating Disorders
(PED) in Inherited Metabolic Diseases (IMD) with dietary treatment between the age of 12
months and 6 years 11 months.
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Jun 18, 2024 | 
inria.hal.science | Raphaël Bergès |Institut de neurophysiopathologie |Assistance Publique |Emilie Denicolaï
Proscillaridin A exerts anti-tumor effects through GSK3β activation and alteration of microtubule dynamics in glioblastoma Origine Fichiers éditeurs autorisés sur une archive ouverte Licence
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Jun 14, 2024 | 
trialbulletin.com | Assistance Publique
OverviewCatastrophizing is a negative evaluation of events. What surgery concerns, pain
catastrophizing is one of the main risks of postoperative pain and / or poor functional
recovery. The best survey to evaluate pain catastrophizing is the PCS (Pain Catastrophizing
Scale). According to the authors, catastrophizers report more negative pain related thoughts,
more emotional distress and more pain than non-catastrophizers.
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Jun 14, 2024 | 
trialbulletin.com | Assistance Publique
OverviewLack of knowledge of digestive absorption of drugs used in metabolic syndrome (MS) before and
after gastric by-pass (GBP) in obese patients. The main objective is to study the changes in
apparent clearance of candesartan, amlodipine, metformin and rosuvastatin, used in the
treatment of metabolic syndrome in obese patients, between the preoperative period and 1 and
6 months after the performance of a GBP.
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Jun 14, 2024 | 
trialbulletin.com | Assistance Publique
OverviewMore than half of all new cases of type 1 diabetes (T1D) are diagnosed in the first decade of
life. It has been reported that early onset T1D may be associated with deterioration in
cognitive performance. It mainly affects working memory or the ability to perform complex
tasks involving planning (executive functions) or decision-making. Brain magnetic resonance
imaging (MRI) has reported alteration brain growth alteration related to impaired cognitive
performance.
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Jun 13, 2024 | 
trialbulletin.com | Assistance Publique
OverviewWe propose to demonstrate that HIV-1 and SARS-CoV-2 are capable of targeting long-lived HSPC
with self-renewal capacities. These progenitors, thus transformed into host cells, can give
rise to a durable source of infected cells with an impact on hematopoiesis.
