Aurelien Dugourd

Jul 17, 2024 | biorxiv.org | Aurelien Dugourd |Pascal Lafrenz |Diego Mañanes |Robin Fallegger

AbstractUnderstanding complex diseases requires approaches that jointly analyze omic data across multiple biological layers, including signaling, gene regulation, and metabolism. Existing data-driven multi-omic analysis methods, such as multi-omic factor analysis (MOFA), can identify associations between molecular features and phenotypes, but they are not designed to integrate existing mechanistic molecular knowledge, which can provide further actionable insights.

Feb 27, 2024 | science.org | Emily Erickson |Hao Cai |Leslie K. Ferrarelli |Inchul You |Grace Perry |Aurelien Dugourd | +11 more

Research ResourceCANCEREmily C. Erickson https://orcid.org/0000-0003-3494-2605, Inchul You, [...] , Grace Perry https://orcid.org/0000-0002-0404-9237, Aurelien Dugourd https://orcid.org/0000-0002-0714-028X, [...] , Katherine A. Donovan https://orcid.org/0000-0002-8539-5106, Claire Crafter https://orcid.org/0000-0001-6566-0868, Jeffrey W. Johannes https://orcid.org/0000-0001-7242-6682, Stuart Williamson https://orcid.org/0000-0002-5209-4796, Jennifer I.

Feb 27, 2024 | science.org | Emily Erickson |Hao Cai |Leslie K. Ferrarelli |Inchul You |Grace Perry |Aurelien Dugourd | +11 more

Research ResourceCANCEREmily C. Erickson https://orcid.org/0000-0003-3494-2605, Inchul You, [...] , Grace Perry https://orcid.org/0000-0002-0404-9237, Aurelien Dugourd https://orcid.org/0000-0002-0714-028X, [...] , Katherine A. Donovan https://orcid.org/0000-0002-8539-5106, Claire Crafter https://orcid.org/0000-0001-6566-0868, Jeffrey W. Johannes https://orcid.org/0000-0001-7242-6682, Stuart Williamson https://orcid.org/0000-0002-5209-4796, Jennifer I.

Nov 24, 2023 | science.org | Qian Bu |Yuki Takada |Manuel F. Ferrer-Garcia |Nadine Kaesler |Aurelien Dugourd |Julio Saez-Rodriguez | +4 more

Mapping cardiac remodeling in chronic kidney diseaseNadine Kaesler https://orcid.org/0000-0001-8097-7660, Mingbo Cheng https://orcid.org/0000-0003-3938-0461, [...] , James Nagai https://orcid.org/0000-0002-7655-7206, James O’Sullivan https://orcid.org/0009-0002-3425-6058, [...] , Fabian Peisker https://orcid.org/0000-0003-0123-8179, Eric M. J.