Barbara E. Bierer

3 weeks ago | trialsjournal.biomedcentral.com | Samuel Byiringiro |Juliana Garcia |Hailey Miller |Evans M. Whitaker |Barbara E. Bierer |Erin D. Michos | +13 more

The lack of diversity in clinical studies has significant ethical and health consequences, limiting the development of effective treatments for diverse populations. Homogeneous participation in clinical studies contributes to health disparities, particularly among historically underrepresented groups in the United States (US). Racial, ethnic, and other minoritized populations have long been excluded from clinical research. In response, the US Congress mandated the National Institutes of Health to assess the impacts of insufficient diversity in clinical studies. Despite efforts by the government, non-profit organizations, and industry players to improve diversity in clinical studies, progress has been slow due to fragmented approaches. For instance, the new US administration (2025) has recently released executive orders which threaten to reverse the progress made in inclusive clinical research. The Stanford Think Tank on Diversity and Equity in Clinical Trials, held in September 2023, brought together key partners across multiple sectors and professions to discuss barriers and explore potential solutions to participation in clinical studies. In this commentary, we discuss the importance of collaborative, inclusive strategies in clinical study design to advance equitable health outcomes for all. Further, we discuss potential implications of the government’s dismissal of diversity, equity, and inclusion initiatives on diverse research participation.

4 weeks ago | nature.com | Anna Anderson |Jodie Bailie |Amy Russell |Barbara E. Bierer |Sharad Philip |Victoria Shepherd

Despite bringing great strengths and facing substantial health inequities, disabled people remain underserved by health research; addressing this requires multi-level actions spanning all areas of research.

Oct 19, 2024 | jamanetwork.com | Barbara E. Bierer

Initially developed in the aftermath of World War II atrocities, the Declaration of Helsinki celebrates its 60th anniversary this year.1 The declaration represents the foundational ethical document addressing the design, conduct, and reporting of medical research, a document referred to internationally.

Oct 19, 2024 | jamanetwork.com | Kirsten Bibbins-Domingo |Linda Brubaker |Greg Curfman |Barbara E. Bierer

Adopted by the 18th WMA General Assembly, Helsinki, Finland, June 1964 29th WMA General Assembly, Tokyo, Japan, October 1975 35th WMA General Assembly, Venice, Italy, October 1983 41st WMA General Assembly, Hong Kong, September 1989 48th WMA General Assembly, Somerset West, Republic of South Africa, October 1996 52nd WMA General Assembly, Edinburgh, Scotland, October 2000 53rd WMA General Assembly, Washington, DC, USA, October 2002 (Note of Clarification added) 55th WMA General Assembly,...

Aug 13, 2024 | tandfonline.com | Carolyn T. Lye |Barbara E. Bierer |Mark Barnes |Minal M. Caron

ABSTRACTThe founders of PubPeer envisioned their website as an online form of a “journal club” that would facilitate post-publication peer review. Recently, PubPeer comments have led to a significant number of research misconduct proceedings – a development that could not have been anticipated when the current federal research misconduct regulations were developed two decades ago.