Bei Yan

Sep 5, 2024 | nature.com | Bei Yan

AbstractStudies have indicated that RAB17 expression levels are associated with tumor malignancy, and RAB17 is more highly expressed in endometrial cancer (EC) tissues than in peritumoral tissues. However, the roles and potential mechanisms of RAB17 in EC remain undefined. The present study confirmed that the expression of RAB17 facilitates EC progression by suppressing cellular ferroptosis-like alterations.

Apr 30, 2024 | mdpi.com | Bei Yan |Jia Luo |Min Zhang |Yi Zhang

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Apr 1, 2024 | pubs.rsc.org | Zhijun Liu |Bei Yan |Huan Liu |Xiao Ying Liu

Enhancing APE-1 detection through apurinic/apyrimidinic site inhibition of DNA polymerase: an innovative, highly sensitive approach This study presents an innovative method for the highly sensitive detection of apurinic/apyrimidinic endonuclease 1 (APE1), a crucial biomarker and target for cancer diagnosis and treatment. This method predicated on our discovery regarding tant the work of Taq DNA polymerase can be blocked by the apurinic or apyrimidinic site (AP site).