Min Zhang

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Articles

Frontiers | Exercise interventions for patients with heart failure: an evidence map

Mar 27, 2025 | frontiersin.org | Tingting Wang |Ling Ji |Jian Li |Min Zhang |Yanyan Hong |Sixuan Han

Background and aimsAlthough exercise performance is an essential tool for managing heart failure, there is still no consensus on whether exercise prescriptio...
Biochemical profiling and structural basis of ADAR1-mediated RNA editing

Mar 17, 2025 | cell.com | Xiangyu Deng |Lina Sun |Min Zhang |Rashmi Basavaraj |Jin Wang |Yi-Lan Weng | +1 more

KeywordsRNA editingADAR1cryo-EMAicardi-Goutières syndromeGet full text accessLog in, subscribe or purchase for full access. References1. Nishikura, K. A-to-I editing of coding and non-coding RNAs by ADARsNat. Rev. Mol. Cell Biol. 2016; 17:83-962. Song, B. ∙ Shiromoto, Y. ∙ Minakuchi, M. ... The role of RNA editing enzyme ADAR1 in human diseaseWIREs RNA. 2022; 13, e16653. Quin, J. ∙ Sedmík, J. ∙ Vukić, D. ... ADAR RNA modifications, the epitranscriptome and innate immunityTrends Biochem. Sci. 2021; 46:758-7714.
Re: Concerns Regarding the Validation of ZYS-1 as a Bona Fide ADAR1 Inhibitor

Mar 7, 2025 | biorxiv.org | Min Zhang |Xiangyu Deng |Yang Gao |Jin Wang

AbstractWang et al. in Nature Cancer report ZYS-1 as an ADAR1 inhibitor and present biochemical and cellular evidence to support ZYS-1's direct interaction with and inhibition of ADAR1, including enzymatic assays, surface plasmon resonance (SPR), drug affinity responsive target stability (DARTS), and cellular thermal shift assays (CETSA). We raise critical methodological concerns regarding the validation of ZYS-1 as a bona fide ADAR1 inhibitor.
RNA-Seq Analysis Reveals Potential Genes Involved in Plant Growth Regulator-Induced Ovary Development in Male Kiwifruit (Actinidia eriantha)

Feb 25, 2025 | mdpi.com | Rong Fu |Min Zhang |Feng Wei |Miaomiao Lin

All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Enhanced Catalytic Performance of Sn Single-Atom Doped CuO with Oxygen Vacancies for Efficient Epoxidation of α-Olefins

Feb 25, 2025 | mdpi.com | Min Zhang |Gaolei Qin |Pengfei Li |Xiangjie Zhang

All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
LLM-KT: Aligning Large Language Models with Knowledge Tracing using a Plug-and-Play Instruction

Feb 5, 2025 | arxiv.org | Jie Zhou |Qin Chen |Min Zhang |Bo Jiang
Identification of glutamine as a potential therapeutic target in dry eye disease - Signal Transduction and Targeted Therapy

Jan 21, 2025 | nature.com | Chuyue Zhang |Min Zhang

AbstractDry eye disease (DED) is a prevalent inflammatory condition significantly impacting quality of life, yet lacks effective pharmacological therapies. Herein, we proposed a novel approach to modulate the inflammation through metabolic remodeling, thus promoting dry eye recovery. Our study demonstrated that co-treatment with mesenchymal stem cells (MSCs) and thymosin beta-4 (Tβ4) yielded the best therapeutic outcome against dry eye, surpassing monotherapy outcomes.
Design and Test of Real-Time Detection System for Cleaning Loss of Rapeseed Harvester

Jan 15, 2025 | mdpi.com | Yao Yang |Min Zhang |Tao Jiang |Gang Wang

1. IntroductionRapeseed is the largest oil crop in China and plays an important role in ensuring the security of the edible oil supply, but the problem of high losses during rapeseed mechanized harvesting is prominent currently [1,2,3,4,5,6]. The high loss rate is an important reason why it is difficult to promote domestic rapeseed harvesting machines at present, and it is also a major problem that hinders the mechanization process of rapeseed harvesting in China.
Hepatitis B virus genotypes A1 and A2 have distinct replication phenotypes due to polymorphisms in the HBx gene

Jan 9, 2025 | journals.plos.org | Min Zhang |Karim Mouzannar |Zhensheng Zhang |Yuji Teraoka |PLOS Pathogens

Loading metrics Open Access Peer-reviewedResearch Article Citation: Zhang M, Mouzannar K, Zhang Z, Teraoka Y, Piotrowski J, Ishida Y, et al. (2025) Hepatitis B virus genotypes A1 and A2 have distinct replication phenotypes due to polymorphisms in the HBx gene. PLoS Pathog 21(1): e1012803.
Persistent but weak magnetic field at the Moon’s midstage revealed by Chang’e-5 basalt

Jan 1, 2025 | science.org | Shuhui Cai |Huafeng Qin |Huapei Wang |Chenglong Deng |Saihong Yang |Ya Xu | +15 more

Research ArticlePLANETARY SCIENCEScience Advances1 Jan 2025Vol 11, Issue 1INTRODUCTIONOrbital and in situ observation magnetic data indicate that the present-day Moon does not have a global magnetic field; nonetheless, large-scale crustal magnetization with maximum local magnetic anomalies at the lunar surface reaching hundreds of nanoteslas suggests the presence of a strong magnetic field in the past (1, 2) (Fig. 1).

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