Ben Van Calster

Jan 22, 2024 | bmj.com | Richard D Riley |Lucinda Archer |Joie Ensor |Ben Van Calster

In 2021, Gupta et al developed the ISARIC 4C deterioration model,23 a multivariable logistic regression model for predicting in-hospital clinical deterioration (defined as any requirement of ventilatory support or critical care, or death) among adults admitted to hospital with highly suspected or confirmed covid-19.

Aug 21, 2023 | nature.com | Paula Dhiman |Ben Van Calster

Protocol development is a crucial step in mapping out any research study. It provides key details on the rationale, objectives, design, data collection, analysis methods and dissemination plans before a piece of research is conducted. Alongside study registration, protocols enhance transparency, replication and research integrity, and foster open-science principles.