Benjamin F Voight

Apr 11, 2024 | healio.com | Michael Monostra |Benjamin F Voight |Marijana Vujkovic |Richard Smith

You've successfully added to your alerts. You will receive an email when new content is published. Click Here to Manage Email Alerts We were unable to process your request. Please try again later. If you continue to have this issue please contact [email protected]. Key takeaways: Researchers identified 145 novel loci associated with the development of type 2 diabetes. Eight mechanistic clusters were formed to link genetic associations with type 2 diabetes complications.

Feb 19, 2024 | nature.com | Konstantinos Hatzikotoulas |Henry Taylor |Xianyong Yin |Kim Lorenz |Mark McCarthy |Anubha Mahajan | +6 more

AbstractType 2 diabetes (T2D) is a heterogeneous disease that develops through diverse pathophysiological processes1,2 and molecular mechanisms that are often specific to cell type3,4. Here, to characterize the genetic contribution to these processes across ancestry groups, we aggregate genome-wide association study data from 2,535,601 individuals (39.7% not of European ancestry), including 428,452 cases of T2D.