Benjamin Shillitoe

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Asymptomatic immunodeficiency-associated vaccine-derived poliovirus infections in two UK children - Nature Communications

Jun 9, 2023 | nature.com | Anika Singanayagam |Cristina C. Celma |Javier Martin |Javier Martín |Benjamin Shillitoe

AbstractIncreasing detections of vaccine-derived poliovirus (VDPV) globally, including in countries previously declared polio free, is a public health emergency of international concern. Individuals with primary immunodeficiency (PID) can excrete polioviruses for prolonged periods, which could act as a source of cryptic transmission of viruses with potential to cause neurological disease.

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