Javier Martin

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Articles

Autoimmune diseases, autoantibody status and silicosis in a cohort of 1238 workers from the artificial stone benchtop industry

Aug 12, 2024 | oem.bmj.com | Dunya Tomic |Ryan F Hoy |Javier Martin |Javier Martín |Jesselyn Sin

AbstractObjectives Autoimmune disorders are multifactorial but occupational exposures have long been implicated, including respirable crystalline silica (RCS). A modern epidemic of silicosis is emerging internationally, associated with dry processing of engineered stone with high (>90%) RCS content. We aimed to investigate the prevalence of clinical autoimmune disease and common autoantibodies in exposed workers.
Molecular subtypes explain lupus epigenomic heterogeneity unveiling new regulatory genetic risk variants - npj Genomic Medicine

Jul 15, 2024 | nature.com | Olivia Castellini-Pérez |Guillermo Barturen |Martin Kerick |Raúl López-Domínguez |Javier Martin |Javier Martín | +3 more

AbstractThe heterogeneity of systemic lupus erythematosus (SLE) can be explained by epigenetic alterations that disrupt transcriptional programs mediating environmental and genetic risk. This study evaluated the epigenetic contribution to SLE heterogeneity considering molecular and serological subtypes, genetics and transcriptional status, followed by drug target discovery.
Evolution of the impact of the COVID‐19 pandemic on heart transplant recipients: Decreasing risk, improving perspective

Feb 20, 2024 | onlinelibrary.wiley.com | Irene Marco |Javier Martin |Javier Martín |Francisco López-Medrano |Andrea Eixerés-Esteve

HTr heart transplant recipients 1 INTRODUCTION The outbreak of the coronavirus disease-2019 (COVID-19) pandemic has posed a global health and social challenge.
Exploration of the circulating human secretome through protein quantitative trait analysis identifies an association between circulating levels of apolipoprotein L1 and risk of giant cell arteritis

Jan 21, 2024 | medrxiv.org | GCA Consortium |Javier Martin |Javier Martín |Natalie Chaddock |Michal Zulcinski

The authors have no conflicts of interest for the work presented in this manuscript. This work was supported in part by the MRC ?Treatment According to Response in Giant cEll arTeritis? (TARGET) Partnership award, MRC DiMeN award, NIHR Leeds Biomedical Research Centre. The MRC TARGET Partnership award supported the salaries of AWM.
De Novo Donor-Specific Antibodies after Heart Transplantation: A Comprehensive Guide for Clinicians

Dec 2, 2023 | mdpi.com | Javier Martin |Javier Martín |Andrea Sanchez |Irene Marco |Esther Mancebo Sierra

All articles published by MDPI are made immediately available worldwide under an open access license. No specialpermission is required to reuse all or part of the article published by MDPI, including figures and tables. Forarticles published under an open access Creative Common CC BY license, any part of the article may be reused withoutpermission provided that the original article is clearly cited. For more information, please refer tohttps://www.mdpi.com/openaccess.
Search Results

Nov 1, 2023 | microbiologyresearch.org | Javier Martin |Javier Martín |Everlyn Kamau |Maël Bessaud |Manasi Majumdar

Enterovirus A71 (EVA71) causes widespread disease in young children with occasional fatal consequences. In common with other picornaviruses both empty capsids (ECs) and infectious virions are produced during the viral lifecycle. While initially antigenically indistinguishable from virions ECs readily convert to an expanded conformation at moderate temperatures.
Wastewater Surveillance in Europe for Non-Polio Enteroviruses and Beyond

Oct 5, 2023 | mdpi.com | Laura Bubba |Soile Blomqvist |Erwin Duizer |Javier Martin |Javier Martín

1. IntroductionEnteroviruses (EVs) are members of the Picornaviridae family, with over 110 types known to infect humans, belonging to species A–D. The most well-known EV is poliovirus (PV), belonging to species C, which can cause acute flaccid paralysis (AFP, also known as polio or poliomyelitis). PV encompasses three serotypes, and thanks to the effort of the Global Polio Eradication Initiative (GPEI) programme, wild-type PV (WPV) is currently only endemic in Afghanistan and Pakistan [].
Superficial versus deep injections of the upper midface-A prospective interventional split‐face study

Aug 18, 2023 | onlinelibrary.wiley.com | Javier Martin |Javier Martín |Lidia Jiménez |Juan Maria Revelles |Nerea Martínez Aznar

1 INTRODUCTION In a recent publication, the term facial biomechanics was introduced by Cotofana and colleagues.1 The authors used this term to describe movements of facial soft tissues occurring during various facial expressions and during facial aging.
Asymptomatic immunodeficiency-associated vaccine-derived poliovirus infections in two UK children - Nature Communications

Jun 9, 2023 | nature.com | Anika Singanayagam |Cristina C. Celma |Javier Martin |Javier Martín |Benjamin Shillitoe

AbstractIncreasing detections of vaccine-derived poliovirus (VDPV) globally, including in countries previously declared polio free, is a public health emergency of international concern. Individuals with primary immunodeficiency (PID) can excrete polioviruses for prolonged periods, which could act as a source of cryptic transmission of viruses with potential to cause neurological disease.

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