Bernard Keavney

Mar 18, 2024 | nature.com | Xiaoguang Xu |Chachrit Khunsriraksakul |James M. Eales |David Talavera |Lida Wang |Abigail C. Lay | +8 more

AbstractGenetic mechanisms of blood pressure (BP) regulation remain poorly defined. Using kidney-specific epigenomic annotations and 3D genome information we generated and validated gene expression prediction models for the purpose of transcriptome-wide association studies in 700 human kidneys. We identified 889 kidney genes associated with BP of which 399 were prioritised as contributors to BP regulation.

Mar 10, 2024 | nature.com | Rodrigo Bonazzola |Enzo Ferrante |Bernard Keavney

AbstractRecent genome-wide association studies have successfully identified associations between genetic variants and simple cardiac morphological parameters derived from cardiac magnetic resonance images. However, the emergence of large databases, including genetic data linked to cardiac magnetic resonance facilitates the investigation of more nuanced patterns of cardiac shape variability than those studied so far.

Mar 10, 2024 | flipboard.com | Rodrigo Bonazzola |Enzo Ferrante |Nishant Ravikumar |Yan Xia |Bernard Keavney |Sven Plein | +2 more

University of South Florida1 hour agoFlorida: A paradise for dunderheadsfloridaphoenix.com - Diane Roberts • 1hHow about this for a new state slogan?