Byrne DP

Jun 24, 2024 | elifesciences.org | Byrne DP |Cristina Olivieri |Yingjie Wang |Caitlin Walker

eLife assessment This important study provides an example of integrating computational and experimental approaches that lead to new insights into the energy landscape of a model kinase. Compelling use of molecular dynamics simulations and NMR spectroscopy provide a conformational description of active and excited states of the kinase; one of which has not been captured in previously solved crystal structures.