Caitlin Clements

Sep 28, 2023 | nature.com | Robert Karlsson |Jie Song |Kaarina Kowalec |Christian Rück |Caitlin Clements |Cathryn M. Lewis | +1 more

AbstractTreatment response and resistance in major depressive disorder (MDD) are suggested to be heritable. Due to significant challenges in defining treatment-related phenotypes, our understanding of their genetic bases is limited. This study aimed to derive a stringent definition of treatment resistance and to investigate the genetic overlap between treatment response and resistance in MDD.