
Caroline M Nievergelt
Articles
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2 months ago |
nature.com | Diego L. Rovaris |Sintia I. Belangero |Sheila T. Nagamatsu |Caroline M Nievergelt |Roseann E. Peterson |Laura Sloofman | +28 more
AbstractPsychiatric disorders are highly heritable and polygenic, influenced by environmental factors and often comorbid. Large-scale genome-wide association studies (GWASs) through consortium efforts have identified genetic risk loci and revealed the underlying biology of psychiatric disorders and traits. However, over 85% of psychiatric GWAS participants are of European ancestry, limiting the applicability of these findings to non-European populations.
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Jan 24, 2025 |
digitalcommons.library.tmc.edu | Jonas Bybjerg-Grauholm |Peter Roy-Byrne |Caroline M Nievergelt |Adam X. Maihofer
KeywordsHumans, Genetic Loci, Genetic Predisposition to Disease, Genome-Wide Association Study, Neurobiology, Polymorphism, Single Nucleotide, Stress Disorders, Post-Traumatic, White People, White, Black or African American, American Indian or Alaska NativeAbstractPost-traumatic stress disorder (PTSD) genetics are characterized by lower discoverability than most other psychiatric disorders. The contribution to biological understanding from previous genetic studies has thus been limited.
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Apr 25, 2024 |
universityofcalifornia.edu | Caroline M Nievergelt |Joseph McClain
The group recently announced their findings from a genome-wide association study of 1,222,822 people in a paper recently published in the journal Nature Genetics. Caroline M. Nievergelt, Ph.D., professor of psychiatry at UC San Diego School of Medicine, is the co-first author on the paper, together with Adam X. Maihofer, PhD., an assistant project scientist in Nievergelt’s lab. PGC-PTSD co-chair Murray B.
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