Jonas Bybjerg-Grauholm

Jan 24, 2025 | digitalcommons.library.tmc.edu | Jonas Bybjerg-Grauholm |Peter Roy-Byrne |Caroline M Nievergelt |Adam X. Maihofer

KeywordsHumans, Genetic Loci, Genetic Predisposition to Disease, Genome-Wide Association Study, Neurobiology, Polymorphism, Single Nucleotide, Stress Disorders, Post-Traumatic, White People, White, Black or African American, American Indian or Alaska NativeAbstractPost-traumatic stress disorder (PTSD) genetics are characterized by lower discoverability than most other psychiatric disorders. The contribution to biological understanding from previous genetic studies has thus been limited.

Dec 18, 2024 | nature.com | Jonas Bybjerg-Grauholm

Oct 8, 2024 | biologicalpsychiatryjournal.com | Jonas Bybjerg-Grauholm

KeywordsTourette syndrometic disorderGWASgeneticgenomicpsychiatricINTRODUCTIONTic disorders (TD; including Tourette syndrome (TS), chronic tic disorder (CTD) and transient tic disorders (TTD)) are childhood-onset neuropsychiatric disorders characterized by recurrent, non-rhythmic tics lasting for at least one year (TS, CTD) or less than a year (TTD; (1)). TS and CTD differ only in the requirement that either motor or vocal tics be present in CTD and that both be present in TS.

May 23, 2024 | science.org | Jonas Bybjerg-Grauholm |Peter Roy-Byrne |W. Brad Ruzicka |Chengyu Deng

Research ArticlePSYCHENCODE2Louise A. Huuki-Myers https://orcid.org/0000-0001-5148-3602, Abby Spangler https://orcid.org/0000-0002-0028-9348, [...] , Nicholas J. Eagles https://orcid.org/0000-0002-9808-5254, Kelsey D. Montgomery https://orcid.org/0000-0001-8420-0138, [...] , Sang Ho Kwon https://orcid.org/0000-0001-5328-0956, Boyi Guo https://orcid.org/0000-0003-2950-2349, Melissa Grant-Peters https://orcid.org/0000-0003-0585-0971, Heena R.

Oct 5, 2023 | nature.com | Robin Beaumont |Christopher Flatley |Marc Vaudel |JING CHEN |Gunn-Helen Moen |Line Skotte | +52 more

AbstractA well-functioning placenta is essential for fetal and maternal health throughout pregnancy. Using placental weight as a proxy for placental growth, we report genome-wide association analyses in the fetal (n = 65,405), maternal (n = 61,228) and paternal (n = 52,392) genomes, yielding 40 independent association signals. Twenty-six signals are classified as fetal, four maternal and three fetal and maternal. A maternal parent-of-origin effect is seen near KCNQ1.