Catherine Verfaillie

Jun 17, 2024 | nature.com | Catherine Verfaillie

Retraction to: Nature https://doi.org/10.1038/nature00870 Published online 20 June 2002 The Editors have retracted this article because concerns have been raised regarding some of the panels shown in Figure 6, specifically: the lower half of Figure 6a (CD45/β-gal) appears to be identical to the upper half of Figure 6e (Gr-1/β-gal) the upper right corner of Figure 6m appears to have two regions that are duplicated within the upper right corner itself The original images for Figures 6a, 6e and...

Mar 27, 2024 | nature.com | Renzo Mancuso |Anna Martinez-Muriana |Emma Davis |Ivana Geric |Baukje Bijnens |Catherine Verfaillie

AbstractMicroglia are central players in Alzheimer’s disease pathology but analyzing microglial states in human brain samples is challenging due to genetic diversity, postmortem delay and admixture of pathologies. To circumvent these issues, here we generated 138,577 single-cell expression profiles of human stem cell-derived microglia xenotransplanted in the brain of the AppNL-G-F model of amyloid pathology and wild-type controls.