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2 weeks ago | 
onlinelibrary.wiley.com | Feng Lan |Beijing Laboratory |Cezmi A. Akdis |Luo Zhang
Biologics are increasingly becoming the treatment of choice for allergic diseases that are unresponsive to standard treatments, such as chronic rhinosinusitis with nasal polyps (CRSwNP), asthma, allergic rhinitis (AR), atopic dermatitis (AD), and prurigo nodularis [1-3]. Key biologics targeting type 2 (T2) inflammation include dupilumab and stapokibart, both of which block interleukin 4 receptor alpha (IL-4Rα) at distinct binding epitopes.
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Oct 6, 2024 | 
einnews.com | Cezmi A. Akdis
Unlocking the epithelial barrier theory: A comprehensive review of the epithelial barrier related 68 diseases Epithelial barrier theory-related diseases, microbial dysbiosis and inflammation These 68 diseases make up to 2 billion patients.
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Sep 23, 2024 | 
journals.plos.org | Josefina Zakzuk |Juan Lopez |Juan López |Cezmi A. Akdis |Luis Caraballo
Loading metrics Open Access Peer-reviewedResearch Article ? This is an uncorrected proof. Citation: Zakzuk J, Lopez JF, Akdis C, Caraballo L, Akdis M. M, van de Veen W (2024) Human Ascaris infection is associated with higher frequencies of IL-10 producing B cells. PLoS Negl Trop Dis 18(9): e0012520.
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Aug 29, 2024 | 
onlinelibrary.wiley.com | Reihane Ziadlou |Ganesh N. Pandian |Jürg Hafner |Cezmi A. Akdis
1 INTRODUCTION Adipose tissue (AT) has traditionally been viewed as an inert energy storage site.1 However, research over the past decades has uncovered its dynamic nature, revealing AT as a highly active organ with metabolic, endocrine, immune, and biomechanical functions.2 AT plays a central role in the pathogenesis of various diseases, including diabetes, cardiovascular disease, osteoarthritis, and cancer.3-5 Situated throughout the body, AT encompasses the deepest layer of the cutaneous...
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Aug 4, 2024 | 
onlinelibrary.wiley.com | Claudia Traidl-Hoffmann |Christine Kühne-Center |Jamie Afghani |Cezmi A. Akdis
AA alopecia areata AD atopic dermatitis AGS galactose-α1,3-galactose (α-Gal) syndrome AMPs antimicrobial peptides AS ankylosing spondylitis CGRP calcitonin gene-related peptide CIDAMPs Cationic Intrinsically Disordered Antimicrobial Peptides CNS central nervous system CRSWNP chronic rhinosinusitis with nasal polyps EE eosinophilic esophagitis ETFAD European Task Force on Atopic Dermatitis EH eczema herpeticum FLG2 filaggrin-2 GAAD Global Atlas on Atopic Dermatitis GAF the 4th Global Allergy...
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Aug 4, 2024 | onlinelibrary.wiley.com | Claudia Traidl-Hoffmann |Christine Kühne-Center |Jamie Afghani |Cezmi A. Akdis
AA alopecia areata AD atopic dermatitis AGS galactose-α1,3-galactose (α-Gal) syndrome AMPs antimicrobial peptides AS ankylosing spondylitis CGRP calcitonin gene-related peptide CIDAMPs Cationic Intrinsically Disordered Antimicrobial Peptides CNS central nervous system CRSWNP chronic rhinosinusitis with nasal polyps EE eosinophilic esophagitis ETFAD European Task Force on Atopic Dermatitis EH eczema herpeticum FLG2 filaggrin-2 GAAD Global Atlas on Atopic Dermatitis GAF the 4th Global Allergy...
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Jul 16, 2024 | 
einnews.com | Cezmi A. Akdis
Effects of environmental pollutants and nutrition on health and performance of athletes Performance and health of professional athletes and physically active people Health and Performance of Athletes Can be Affected by Epıthelıal Barrıers and Microbiome”DAVOS, SWITZERLAND, July 16, 2024 /EINPresswire.com/ -- Athletes' health - effects of environmental pollutants and nutrition on epithelial barrier function and healthy microbes in the body The health of athletes and physically active people is...
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Jun 23, 2024 | 
onlinelibrary.wiley.com | Ioana Agache |Marek Jutel |Cezmi A. Akdis
Planetary health and human health are interconnected.
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Nov 20, 2023 | 
onlinelibrary.wiley.com | Magdalena Zemelka-Wiacek |Ioana Agache |Cezmi A. Akdis |Mübeccel Akdis
1 INTRODUCTION Allergen immunotherapy (AIT) was initially reported at the beginning of the 20th century and performed in clinical routine for more than 110 years.1 A high level of evidence for its efficacy and safety has been elaborated throughout the recent decades for various forms of application, sublingual (SLIT) and subcutaneous (SCIT), as well as oral immunotherapy (OIT), the latter being used in managing food allergies, especially peanut, cow's milk and hen's egg allergy (Table 1).2-7...
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Nov 4, 2023 | 
onlinelibrary.wiley.com | Arthur Helbling |Marek Jutel |Cezmi A. Akdis |Oliver Hausmann
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