Changchun Wang

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Articles

Elevated IL-22 as a result of stress-induced gut leakage suppresses septal neuron activation to ameliorate anxiety-like behavior

Dec 6, 2024 | cell.com | Mengyu Xia |Junmei Lu |Jiabin Lan |Rani Shiao |Hongbin Sun |Zheyu Jin | +14 more

Keywordsinterleukin-22psychological stressseptal neuronsgut leakageTH17anxietydepressionthe septal areaIntroductionPsychological stress is a major etiological inducer of mood disorders such as anxiety disorders and depression. Stress-related psychological diseases impact about 10% of the world population, but prevalence also increases sharply during difficult times such as the COVID-19 pandemic, according to the World Health Organization.
Genomic and transcriptomic remodelling by neoadjuvant chemoradiotherapy (nCRT) and indicative role of acquired INDEL percentage for nCRT efficacy in esophageal squamous cell carcinoma

Jun 18, 2023 | redjournal.org | Tingting Feng |Xiaojun Fan |Changchun Wang

: The impact of genomic factors on the response of patients with esophageal squamous cell carcinoma (ESCC) to neoadjuvant chemoradiotherapy (nCRT), as well as how nCRT influences the genome and transcriptome of ESCC, remain largely unknown. : 137 samples from 57 ESCC patients undergoing nCRT were collected and subjected to whole-exome sequencing and RNA-seq analysis.

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