Chao Zheng

2 months ago | nature.com | Chao Zheng

AbstractThe potential benefits of pyrotinib for patients with trastuzumab-insensitive, HER2-positive early-stage breast cancer remain unclear. This prospective, multicentre, response-adapted study evaluated the efficacy and safety of adding pyrotinib to the neoadjuvant treatment of HER2-positive breast cancer patients with a poor response to initial docetaxel plus carboplatin and trastuzumab (TCbH). Early response was assessed using magnetic resonance imaging (MRI) after two cycles of treatment.

Dec 2, 2024 | nutritionandmetabolism.biomedcentral.com | Hui Wang |Yuxin Chen |Yang Chen |Yixi Xu |Xiaoyu Zhang |Qingyang Mao | +7 more

This investigation adopted a two-center case–control study in China. Detailed information about the study design and participant recruitment can be found in our previous publications [17,18,19]. In brief, the present study comprised 195 patients diagnosed with type 2 diabetes mellitus (T2DM), of which 83 exhibited DR and 112 did not.

Jun 5, 2024 | science.org | Yang Wang |Mohammed R. Shaker |Ahmed N. Hegazy |Chao Zheng

Research Article HEALTH AND MEDICINE Chao Zheng https://orcid.org/0000-0002-4313-2308, Wen Zhang, [...] , Xiang Gong, Fengqin Xiong, [...] , Linyang Jiang, Lingli Zhou, Yuan Zhang, Helen He Zhu https://orcid.org/0000-0003-0290-5527, Hao Wang https://orcid.org/0009-0003-8923-7353 [email protected], [...] , Yaping Li https://orcid.org/0000-0002-0574-6966 [email protected], and Pengcheng Zhang https://orcid.org/0000-0002-4546-0022 [email protected]+8 authors +6 authors +1 authors...

Mar 19, 2024 | nature.com | Min Zhu |Chao Zheng

AbstractMedium-sized-ring compounds have been recognized as challenging synthetic targets in organic chemistry. Especially, the difficulty of synthesis will be augmented if an E-olefin moiety is embedded. Recently, photo-induced dearomative cycloaddition reactions that proceed via energy transfer mechanism have witnessed significant developments and provided powerful methods for the organic transformations that are not easily realized under thermal conditions.

Feb 28, 2024 | nature.com | Chao Zheng

AbstractThe macro petrographic compositions and its pore characteristics of coal reservoir play critical role in the accumulation and development of coalbed methane (CBM). In this paper, the pore characteristics of vitrain and durain were analyzed through the experiment and fractal theory. The results indicated that the micropores and microfractures develop in vitrain, and that transitional pores develop in durain.