
Articles
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3 weeks ago |
biorxiv.org | Christine Lim |John Hardy |Michele Vendruscolo
AbstractAmyloid plaques and neurofibrillary tangles are molecular hallmarks of Alzheimer's disease. According to the amyloid cascade hypothesis, aberrant Aβ and tau behaviours contribute synergistically to accelerate the Alzheimer's pathology. However, the complex molecular mechanisms linking Aβ and tau dysregulation remain to be fully characterised. To address this problem, we investigated the connection between Aβ and tau through the protein homeostasis (proteostasis) network.
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Nov 16, 2024 |
bernama.com | Christine Lim
By Christine Lim KUALA LUMPUR, Nov 17 (Bernama) -- Malaysia is in a position to demonstrate leadership in ASEAN as the country assumes its chairmanship role next year. Japan External Trade Organisation (Jetro) Kuala Lumpur managing director Koichi Takano said there are expectations and trust in Malaysia’s leadership.
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Nov 15, 2024 |
biorxiv.org | Christine Lim |Yuqi Bian |Alicia Gonzalez-Diazag |Frank W. Pun
AbstractMembraneless organelles (MLOs) are dynamic macromolecular condensates that act as crucibles to modulate biological process within the cell. Since MLOs form in the absence of lipid membranes, it is important to understand how their effective regulation is achieved by the protein homeostasis (proteostasis) system. To address this question, we report a comprehensive mapping of the proteostasis network (PN) of MLOs, comprising over 220,000 protein-protein interactions.
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Sep 27, 2024 |
bernamabiz.com | Christine Lim
• 27/09/2024 03:21 PM By Christine Lim KUALA LUMPUR, Sept 27 (Bernama) -- Former developer of Angry Birds online gaming franchise Peter Vesterbacka sees potential in the education and entertainment industries in Malaysia. The Finnish entrepreneur said there is room for start-up entrepreneurship to grow in Malaysia and he is prepared to harness the various possibilities.
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Sep 26, 2024 |
bernama.com | Christine Lim
By Christine Lim KUALA LUMPUR, Sept 27 (Bernama) -- Former developer of Angry Birds online gaming franchise Peter Vesterbacka sees potential in the education and entertainment industries in Malaysia. The Finnish entrepreneur said there is room for start-up entrepreneurship to grow in Malaysia and he is prepared to harness the various possibilities.
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