CHRU Tours

Oct 4, 2023 | karger.com | CHRU Tours

Background: Vascular anomalies (VAs) are increasingly being treated with PI3K/AKT/mTOR pathway inhibitors. These drugs have immunosuppressive properties and thus theoretically overexpose patients to opportunistic infections, especially Pneumocystis jirovecii pneumonia (PJP). PJP prophylaxis use lacks consensus. We aimed to investigate the prevalence of PJP in patients receiving mTOR/PI3K/AKT inhibitors for VAs and determine any indication for pneumocystis prophylaxis in this population.

Jun 22, 2023 | ccforum.biomedcentral.com | CHRU Tours |Médecine Intensive Réanimation |Université de Tours

Severe ABI refers to a sudden event that results in brain damage and reduced perfusion leading to reduced alertness. ABI is heterogeneous and covers different subtypes, notably traumatic brain injury (TBI), subarachnoid hemorrhage (SAH), intracranial bleeding and hypoxic ischemic brain injury.