Chu Rouen

Sep 25, 2024 | aacrjournals.org | Chu Rouen

Wilms tumors are commonly associated with predisposition syndromes many, but not all, of which include overgrowth. Several of these syndromes also include a risk of other embryonal malignancies – particularly hepatoblastoma. Guidelines for surveillance in this population were published in 2017 and recently members of the AACR Pediatric Cancer Working Group met to update those guidelines with a review of more recently published evidence and risk estimates.

Aug 4, 2024 | link.springer.com | Institut du Cerveau |Chu Rouen

AbstractPhysical activity combined with virtual reality and exergaming has emerged as a new technique to improve engagement and provide clinical benefit for gait and balance disorders in people with Parkinson’s disease (PD). To investigate the effects of a training protocol using a home-based exergaming system on brain volume and resting-state functional connectivity (rs-FC) in persons with PD.

Aug 2, 2024 | academic.oup.com | Chu Rouen

After restorative rectal resection, up to 80% of patients report bowel dysfunction with wide ranging symptoms including faecal incontinence, urgency, frequent bowel movements, and/or evacuatory dysfunction1. This combination of symptoms is known as low anterior resection syndrome (LARS)1. Although frequently transient, LARS persists after the first 2 years in about half of operated patients, leading to severe impairment of quality of life2.

Jul 30, 2024 | aacrjournals.org | Sun Young |Chu Rouen

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Jan 16, 2024 | karger.com | Chu Rouen

Introduction: Sanfilippo syndrome or mucopolysaccharidosis type 3 (MPS-3) is a rare condition and its epidemiological data are still not defined. MPS-3 is linked to a deficiency in enzymes involved in heparan sulfate degradation. This biomolecule is neurotoxic and its accumulation underlies the severe central nervous system degeneration observed in this disease. Methods: Here, we describe 15 Turkish patients with MPS-3A or MPS-3B subtypes.