Chuanyu Liu

Jan 10, 2025 | nature.com | Chuanyu Liu

AbstractIschemic stroke constitutes a multifaceted neurological affliction that spans various cellular types. Lack of dynamic chromatin accessibility data after stroke is one of the obstacles to understanding this process.

Feb 25, 2024 | nature.com | Dan Zhang |Chuanyu Liu |Wenhao Zhou

AbstractHuman cerebellum encompasses numerous neurons, exhibiting a distinct developmental paradigm from cerebrum. Here we conducted scRNA-seq, scATAC-seq and spatial transcriptomic analyses of fetal samples from gestational week (GW) 13 to 18 to explore the emergence of cellular diversity and developmental programs in the developing human cerebellum. We identified transitory granule cell progenitors that are conserved across species.

Jun 7, 2023 | frontiersin.org | Chuanyu Liu

Single-cell chromatin accessibility profiling of cell-state-specific gene regulatory programs during mouse organogenesis Chuanyu Liu1* , Qiuting Deng2 , Shengpeng Wang2 , Zijie Huang1, Qing Lan1 , Guangyao Lai1, Jiangshan Xu1 , Yue Yuan1 , Chang Liu1, Xiumei Lin2, Weimin Feng2, Wen Ma1, Mengnan Cheng1 , Shijie Hao2 , Shanshan Duan1, Huiwen Zheng1 , Xiaoyan Chen1, Yong Hou1 , Yingjie Luo1* and Longqi Liu1* 1Beijing Genomics Institute (BGI), China 2College of Life Sciences, University of...