Chutong Zhong

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Mammalian Cell Models of the Distal Convoluted Tubule: A Systematic Review of Cell Lines, Culture Condition and Gene Expression

Feb 23, 2024 | biorxiv.org | Zhen Sun |Stephen Walsh |Chutong Zhong |Alessandra Grillo

AbstractThis review examines the crucial role of human cellular models in renal physiology research, with a specific focus on the distal convoluted tubule (DCT). It aims to provide a comprehensive summary of the origins, culture practices, and genetic studies associated with commonly employed DCT cell models. To achieve this, a systematic literature review was performed on Europe PMC, employing a Boolean search strategy.

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