Cihan Oguz

Dec 11, 2024 | nature.com | Inta Gribonika |Verena M. Link |Eduard Ansaldo |Cihan Oguz |Djenet Bousbaine |Michael Fischbach

AbstractThe microbiota colonizes each barrier site and broadly controls host physiology1. However, when uncontrolled, microbial colonists can also promote inflammation and induce systemic infection2. The unique strategies employed at each barrier tissue to control the coexistence of the host with its microbiota remain largely elusive. Here we uncover that, within the skin, host-microbiota symbiosis depends on the remarkable ability of the skin to act as an autonomous lymphoid organ.