CJ Cambier

Nov 28, 2023 | biorxiv.org | Tan-Yun Cheng |Kubra F. Naqvi |Lindsay E. Guzman |CJ Cambier

AbstractSurface lipids on pathogenic mycobacteria modulate infection outcomes by regulating host immune responses. Phenolic glycolipid (PGL) is a host-modulating surface lipid that varies among clinical Mycobacterium tuberculosis strains. PGL is also found in Mycobacterium marinum where it promotes infection of zebrafish through effects on the innate immune system.