Tan-Yun Cheng

Nov 28, 2023 | biorxiv.org | Tan-Yun Cheng |Kubra F. Naqvi |Lindsay E. Guzman |CJ Cambier

AbstractSurface lipids on pathogenic mycobacteria modulate infection outcomes by regulating host immune responses. Phenolic glycolipid (PGL) is a host-modulating surface lipid that varies among clinical Mycobacterium tuberculosis strains. PGL is also found in Mycobacterium marinum where it promotes infection of zebrafish through effects on the innate immune system.

Nov 28, 2023 | dx.doi.org | Lindsay E. Guzman |C. J. Cambier |Tan-Yun Cheng |Kubra F. Naqvi

Download Hi-Res ImageDownload to MS-PowerPointCite This:ACS Chem. Biol. 2024, XXXX, XXXRETURN TO ARTICLES ASAPPREVArticlesNEXTLindsay E. GuzmánStanford Sarafan ChEM-H, Stanford University, Stanford, California 94305, United StatesDepartment of Chemistry, Stanford University, Stanford, California 94305, United States, C. J.

May 18, 2023 | biorxiv.org | Heather J. Faust |Tan-Yun Cheng |Ilya Korsunsky |Gerald Watts

AbstractFibroblasts play critical roles in tissue homeostasis, but in pathologic states can drive fibrosis, inflammation, and tissue destruction. In the joint synovium, fibroblasts provide homeostatic maintenance and lubrication. Little is known about what regulates the homeostatic functions of fibroblasts in healthy conditions.