Clémence Leyrat

2 months ago | onlinelibrary.wiley.com | Katy Morgan |Ian White |Clémence Leyrat |Simon J Stanworth

1 Introduction Non-inferiority (NI) trials aim to show a new treatment is not worse than a standard treatment by more than a pre-defined amount (the non-inferiority margin) [1-3]. NI trials are often used in settings where a new treatment may not improve outcomes compared to a standard treatment but is expected to have other benefits such as reduced cost or an improved safety profile.

Aug 16, 2023 | jamanetwork.com | Jeremy Brown |Kevin Wing |Clémence Leyrat |Stephen Evans

Association Between Fluoroquinolone Use and Hospitalization With Aortic Aneurysm or Aortic Dissection Key PointsQuestion  Is fluoroquinolone use associated with an increase in risk of hospitalization with aortic aneurysm or aortic dissection?