Clémence Leyrat

1 week ago | dialnet.unirioja.es | Kevin Wing |Clémence Leyrat

Ayuda Buscar en la ayuda Buscar en la ayuda Improving the validity of noninterventional comparative effectiveness research by basing study design on a specified existing randomized controlled trial Wing, Kevin [1] ; Leyrat, Clémence [2] [1] Public Health, School of Health and Wellbeing, University of Glasgow, Glasgow, United Kingdom [2] Department of Medical Statistics, Faculty of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine, London, United Kingdom...

Feb 7, 2025 | onlinelibrary.wiley.com | Katy Morgan |Ian White |Clémence Leyrat |Simon J Stanworth

1 Introduction Non-inferiority (NI) trials aim to show a new treatment is not worse than a standard treatment by more than a pre-defined amount (the non-inferiority margin) [1-3]. NI trials are often used in settings where a new treatment may not improve outcomes compared to a standard treatment but is expected to have other benefits such as reduced cost or an improved safety profile.

Aug 16, 2023 | jamanetwork.com | Jeremy Brown |Kevin Wing |Clémence Leyrat |Stephen Evans

Association Between Fluoroquinolone Use and Hospitalization With Aortic Aneurysm or Aortic Dissection Key PointsQuestion  Is fluoroquinolone use associated with an increase in risk of hospitalization with aortic aneurysm or aortic dissection?