Clinical Informatics

May 24, 2024 | thelancet.com | Rachel Byford |Mome Mukherjee |Cecilia Okusi |Clinical Informatics

SummaryThere were substantial reductions in asthma exacerbations during the COVID-19 pandemic for reasons that remain poorly understood. We investigated changes in modifiable risk factors which might help explain the reductions in asthma exacerbations.

May 23, 2024 | academic.oup.com | Molecular Biosciences |Clinical Informatics |Carlos H M

Protein–protein interactions (PPIs) are fundamental to many cellular processes, making them important targets for therapeutic intervention and critical focus in the study of various diseases. PPI sites contain critical areas known as hotspots, which are crucial for the strength and specificity of the interactions (1,2). The stability of these PPIs is vital for cellular equilibrium and the regulation of complex biological activities (3,4).

May 2, 2024 | aacrjournals.org | Biomedical Informatics |Clinical Informatics

Increasingly, research demonstrates economic benefits of tobacco cessation in cancer care, as seen in a new study by Kypriotakis and colleagues of the MD Anderson cessation program, demonstrating median health care cost savings of $1,095 per patient over 3 months.

Oct 23, 2023 | onlinelibrary.wiley.com | Clinical Informatics |Molecular Biosciences |David Ascher

1 INTRODUCTION Proteins mediate a range of critical biological functions in the cell, such as the transport of molecules in and out,1 identification of pathogens and recruitment of T-cells to kill them,2 and cell growth,3, 4 via tightly coordinated interactions with other molecules. Understanding of the molecular mechanisms of how the different molecules interact represents an attractive way of potentially utilize these interacting interface regions for the development of new drugs.