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Jan 5, 2025 | 
alzres.biomedcentral.com | Clinical Neurosciences
Two GWAS summary statistics data were used to generate polygenic scores: (a) a GWAS [9] that was an extension to the International Genomics of Alzheimer’s Project (IGAP) [20] with 21,982 clinically diagnosed AD cases and 41,944 controls (AD) and (b) a meta-analyzed GWAS [10] of the European Alzheimer & Dementia Biobank (EADB) consortium dataset with the UK Biobank (UKBB) data including 39,106 clinically diagnosed AD cases, 46,828 proxy-AD cases and 401,577 population-based controls (ADRD).
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Nov 27, 2024 | .html&sz=64)
fis.tu-dresden.de | Markus J. Martin |Clinical Neurosciences |Lena Beume |Kai Nitschke
Abstract KeywordsAged, Brain Mapping, Case-Control Studies, Cerebral Cortex/physiology, Female, Functional Laterality, Humans, Imitative Behavior/physiology, Magnetic Resonance Imaging, Male, Middle Aged, Motor Cortex/physiology, Neuropsychological Tests, Parietal Lobe/physiology, Psychomotor Performance/physiology, Stroke/physiopathology
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Oct 18, 2024 | 
jmedicalcasereports.biomedcentral.com | Clinical Neurosciences
ReferencesAl-Enezi E, Alghamdi M, Al-Enezi K, AlBalwi M, Davies W, Al-Enezi WE. Helsmoortel-Van der Aa syndrome in a 13-year-old girl with autistic spectrum disorder, dysmorphism, a right solitary kidney, and polycystic ovaries: a case report. J Med Case Rep. 2024;18:422. https://doi.org/10.1186/s13256-024-04746-2. Article PubMed Central Google Scholar Pascolini G, Agolini E, Majore S, Novelli A, Grammatico P, Digilio MC.
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Sep 29, 2024 | 
bmcpsychiatry.biomedcentral.com | Clinical Neurosciences
The RCT will be conducted remotely and participants from all regions of Lithuania, both rural and urban, will be invited to take part. The intervention will be delivered online via the Spring web app, and guidance sessions with psychologists will be held online. A three-step screening procedure will evaluate eligibility. Inclusion and exclusion criteria will initially be assessed through self-report measures.
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Sep 13, 2024 | 
pn.bmj.com | Neil Scolding |Clinical Neurosciences
CLINICAL NEUROLOGYIt goes without saying that the words ‘anorak’ and ‘neurologist’ should never appear in close proximity—but we do like our diseases to behave in an orderly and seemly fashion. The correct clinical pace is important: progression over minutes to hours for strokes, days to weeks for inflammation and infection, weeks to months for tumours, months to years for neurodegeneration. Transgressing these rules is neither welcome nor helpful diagnostically (nor, sadly, rare).
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Sep 12, 2024 | 
pn.bmj.com | Lu Yang |Neil Scolding |Claire Rice |Clinical Neurosciences
FootnotesContributors LY: initial draft of the manuscript and subsequent revisions, figure creation. RJPS: specialist neuroradiology input. NJS: review of manuscript. CMR: concept for manuscript, review of manuscript and figure creation, guarantor. Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors. Competing interests None declared.
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Sep 6, 2024 | 
academic.oup.com | Clinical Neurosciences
Empathy determines our emotional and social lives. Research has recognised the role of the right temporo-parietal junction (rTPJ) in social cognition, however there is less direct causal evidence for its involvement in empathic responses to pain, which is typically attributed to simulation mechanisms.
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Sep 4, 2024 | 
jmedicalcasereports.biomedcentral.com | Clinical Neurosciences
The 13-year-old Saudi girl was initially referred at the age of 10 years to the clinical genetic and metabolic disorder clinic in King Abdullah Specialist Children’s Hospital, Riyadh, after presenting with dysmorphic features, severe mental retardation, ASD, and ADHD, according to the mental health professional clinic evaluation. In addition, she complained of sleep disturbances and frequent apnea attacks.
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Aug 22, 2024 | 
onlinelibrary.wiley.com | Mohammed Almuqbil |William Davies |Clinical Neurosciences |Najlaa A. Alsubeeh
CONFLICT OF INTEREST STATEMENT AB-A, SA, and EZ are employees of CENTOGENE GmbH. All other authors declare no conflicts of interest. REFERENCES , , , , , , , , , , , , , , , , , , , … (2021). Successful application of genome sequencing in a diagnostic setting: 1007 index cases from a clinically heterogeneous cohort. European Journal of Human Genetics, 29(1), 141–153. , , , , , , , , , , , , , , , , , , , … (2013).
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Aug 16, 2024 | 
physoc.onlinelibrary.wiley.com | Donovan Smith |Clinical Neurosciences |Biomedical Engineering
Journal Club Postganglionic cholinergic collaterals drive pathological sympathetic hyperactivity Donovan Bernard Smith, Corresponding Author Donovan Bernard Smith Departments of Physiology and Pharmacology, Cardiac Sciences, Clinical Neurosciences, Biomedical Engineering, Libin Cardiovascular Institute, Hotchkiss Brain Institute, RESTORE.network, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada Email: [email protected] Search for more papers by this author...
