Clinton J. Bradfield

Nov 27, 2024 | nature.com | Julia Gross |Clinton J. Bradfield |John P. Dekker |David Weiss

AbstractThe immunologic consequences of using bactericidal versus bacteriostatic antibiotic treatments are unclear. We observed a bacteriostatic (growth halting) treatment was more protective than a bactericidal (bacteria killing) treatment in a murine peritonitis model. To understand this unexpected difference, we compared macrophage responses to bactericidal treated bacteria or bacteriostatic treated bacteria.

Mar 1, 2024 | blog.sciencenet.cn | Shiwei Zhu |Clinton J. Bradfield |Xingxing KUANG

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Mar 1, 2024 | sciencemag.org | Shiwei Zhu |Xingxing KUANG |Jens Westermann |Clinton J. Bradfield

Supplementary MaterialsFigs. S1 to S13Tables S1 to S4MDAR Reproducibility ChecklistReferences and Notes1F. Randow, J. D. MacMicking, L. C. James, Cellular self-defense: How cell-autonomous immunity protects against pathogens. Science 340, 701–706 (2013). 2J. D. Jones, R. E. Vance, J. L. Dangl, Intracellular innate immune surveillance devices in plants and animals. Science 354, aaf6395 (2016). 3M. Shi, P. Zhang, S. M. Vora, H.