Julia Gross

Nov 27, 2024 | nature.com | Julia Gross |Clinton J. Bradfield |John P. Dekker |David Weiss

AbstractThe immunologic consequences of using bactericidal versus bacteriostatic antibiotic treatments are unclear. We observed a bacteriostatic (growth halting) treatment was more protective than a bactericidal (bacteria killing) treatment in a murine peritonitis model. To understand this unexpected difference, we compared macrophage responses to bactericidal treated bacteria or bacteriostatic treated bacteria.